5/11/2023 0 Comments Sylaps scopolamineWhat drugs interact with Transderm Scop (scopolamine)? Drugs Causing Central Nervous System (CNS) Adverse Reactions Skin and subcutaneous tissue disorders: rash generalized, skin irritation, erythema General disorders and administration site conditions: application site burningĮye disorders: dry eyes, eye pruritus, angle-closure glaucoma, amblyopia, eyelid irritation Nervous system disorders: headache, amnesia, coordination abnormalities, speech disorder, disturbance in attention, restlessness Psychiatric disorders: acute psychosis including: hallucinations, disorientation, and paranoia Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The following adverse reactions have been identified during post-approval use of scopolamine transdermal system. *occurring in at least 3% of patients and at a rate higher than placebo Table 1 Common Adverse Reactions* in Surgical Patients for the Prevention of PONV PONVĬommon adverse reactions, occurring in at least 3% of patients in PONV clinical trials are shown in Table 1. Less common adverse reactions, included drowsiness (less than one sixth), blurred vision and dilation of the pupils. The most common adverse reaction (approximately two thirds) was dry mouth. The following serious adverse reactions are described elsewhere in labeling:īecause clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Transderm Scop (scopolamine) side effects list for healthcare professionals Consult your doctor before breastfeeding. Use of Transderm Scop in pregnant women has not been adequately evaluated. antihistamines (including meclizine ),.Transderm Scop slows passage of materials including drugs through the stomach and intestines and may reduce the absorption of some drugs.ĭrugs that have anticholinergic effects such as the following increase the anticholinergic side effects of Transderm Scop: Some patches may cause burns of the skin if worn during a magnetic resonance imaging ( MRI) scan.ĭrug interactions of Transderm Scop include alcohol, tranquilizers, sedatives, and other drugs that cause drowsiness which may worsen the drowsiness caused by Transderm Scop. If used more than 3 days some patients may experience withdrawal symptoms such as Serious side effects of Transderm Scop include: Scopolamine must be taken before the onset of motion sickness to be effective.Ĭommon side effects of Transderm Scop include:.Scopolamine also may work directly on the vomiting center. Scientists believe that scopolamine prevents communication between the nerves of the vestibule and the vomiting center in the brain by blocking the action of the neurotransmitter acetylcholine (anticholinergic effect).When a person susceptible to motion sickness experiences motion, the vestibule sends a signal through nerves to the vomiting center in the brain, and vomiting occurs. The vestibular part of the ear is important for balance. It is not clear how scopolamine prevents nausea and vomiting due to motion sickness.Scopolamine is absorbed into the body through the skin. Transderm Scop is administered topically (through the skin or transdermally) via a special delivery system that gradually releases scopolamine onto the skin over a period of three days.Transderm Scop ( scopolamine) is an anticholinergic drug patch used to prevent motion sickness. Does Transderm-Scop (scopolamine) cause side effects?
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